PAPERS

Predictions

Using a large amount of diploid yeast strains, we predict growth phenotypes from family information, segregating genetic variants and other phenotypes with accuracy that exceeds narrow-sense heritability

Nature Communications
2016

Phenotyping

We put forward a novel high through-put microbial phenomics framework for monitering microbe growth on solid agar plates with high accuracy and resolution

G3
2016

Variation

We device Phased Outbred Lines (POLs) and go on to offer the most complete dissection of complex traits in a diploid genetic system to date

Nature Communications
2016

Divergence

By sequencing strains from domesticated and wild yeasts using the PacBio technique we give a comprehensive view of the differing genome dynamics of two Saccharomyces species.

Nature Genetics
2017

Evolution

What is more important in adaption, de novo mutations or genetic background? Here we evolve yeast populations from non-isogenic backgrounds to find out.

Cell Reports
2017

Novelties

De novo genes are gaining ground as an important contributor to evolution, read about how we investigated their emergence in natural S. paradoxus strains.

Genome Research
2019

Levels

This review features de novo genes, gene duplicates, speciation, networks, emergent traits, and species and genome conflicts! (It does not feature all of the organisms in this image, not to scale..)

Evolutionary applications
2020

Aging

This paper characterizes the genetic cause of an aging phenotype found in natural strains of S. cerevisiae.

Genome Research
2020

Assimilation

I contributed with QTL mapping to this interesting project where the Braendle group found a strain of C. elegens where a plastic trait had been genetically assimilated!

Science Advances
2021

Genomic shock

Using transriptomics data from other publications, we tested the genomic shock hypothesis in yeast.

Frontiers in Fungal Biology
2021